228645 - Leukaemia: Drugs (Answered)

Mark Tami
To ask the Secretary of State for Health, what assessment he has made of the drugs available for chronic myeloid leukaemia patients who are intolerant or resistant to tyrosine-kinase inhibitor therapies.

George Freeman

The National Institute for Health and Care Excellence (NICE) considered the suitability of ponatinib for the treatment of chronic myeloid leukaemia for referral to its technology appraisal work programme through the topic selection process in 2013-14. NICE concluded, following consultation with stakeholders, that a technology appraisal was not appropriate, noting that the likely eligible patient population was very small. Further information on the rationale for not referring this topic to NICE is available on the NICE website at:


A number of treatments, including the drug bosutinib, are available through the Cancer Drugs Fund for patients with chronic myeloid leukaemia who are intolerant or resistant to other tyrosine-kinase inhibitor therapies.